Nov 17, 2021
I attended a Zoom meeting hosted by the FVMA with the presenter Dr. Jane Manfredi of Michigan State. The title of her talk was "Quick On Their Feet: Endocrine Disease And The Equine Athlete." Unfortunately, I arrived a few minutes late. Still, this presentation was on equine metabolic syndrome (EMS), PPID/Cushing's Disease in horses, insulin resistance/dysregulation and other points.
I reviewed her presentation, discussing the good points, and, once again, disappointed in the lack of prominence in discussing diet; some of the information there needed updating with human investigations. She advised diagnosing early and getting the horse on an effective treatment based on lab work and flow diagrams. For this, Dr. Manfredi did an excellent job.
What makes this podcast interesting is her association of EMS with joint pain in horses using data extrapolated from human studies. The association she made was good. She also mentions the importance of the proportions of bacteria living in the gut microbiome in having the horse be thin, just right or obese. This relationship is in rats as well as humans.
Further, Dr. Manfredi includes her opinion and studies of using a blend of polyphenols (specifically resveratrol) with a mix of amino acids to reduce general and joint inflammation (osteoarthritis). What made this point so strong for me was a podcast I had listened to the day before where a legend in the field of human functional medicine had also said how effective adding the polyphenols resveratrol and curcumin was in reducing inflammation. By the way, Wikipedia says there is no evidence of this effect with resveratrol. So there is more to discover.
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